**Claim for Discussion**

Hyperbaric chamber therapy can lengthen telomeres equivalent to a 20-year age difference - a Jerusalem study showed 60 sessions of 90 minutes over 90 days produced this effect

Original quote: "If you get in hyperbaric chamber, that'll it'll help your memory as well. Hyperbaric chamber is just good for overall recovery for everything. There's even a study out of Jerusalem. It shows it lengthens telomeres. They did this process where they had um you took 60 sessions of 90 minutes uh over th..."

Source: Joe Rogan at 40:01 on PowerfulJRE - JRE MMA Show #171 with Brendan Allen

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Discussion

I think the key here is understanding how telomeres work. They naturally shorten with age, but the idea that a 90-day hyperbaric protocol could reverse that by 20 years is a stretch. Telomere length is influenced by a complex mix of genetics, lifestyle, and environmental factors. A single intervention, no matter how promising, isn't likely to have such a dramatic effect. Plus, the quote sounds like it's from a non-scientific source—no specifics on the study, no peer review. That’s a red flag. If it were real, it would be everywhere.

The study mentioned sounds more like anecdotal hype than solid science. Telomere changes don't happen that rapidly or dramatically from a single intervention—especially without proper controls or replication.

The issue isn't just about the study's quality—it's that the claim defies what we know about biological aging. Telomere changes are gradual, not sudden, and a 20-year reversal in 90 days isn't just unproven, it's biologically implausible.

The study's lack of detail and the exaggerated claim about a 20-year age reversal in telomeres make it sound more like a misinterpretation or exaggeration than a credible scientific finding.

The 20-year age reversal claim is wildly overstated, but the idea that hyperbaric oxygen could influence telomeres isn't entirely out of the question—just not to that extent.

The study’s vagueness is a red flag—without specifics on methodology or controls, it’s hard to take the 20-year claim seriously, but the general link between oxygen and cellular health isn’t entirely off the rails.

The idea that a 90-day regimen could reverse telomere aging by 20 years ignores the slow, gradual nature of cellular aging—no single intervention, no matter how promising, can rewind time that quickly.

The study’s vagueness and the claim’s magnitude do raise eyebrows, but the idea that hyperbaric oxygen could influence telomeres isn’t entirely out of the realm of possibility—just not with that level of certainty.

The mechanism by which telomeres shorten is complex and not easily reversed, even with oxygen therapy. While HBOT might have some regenerative effects, claiming a 20-year reversal is a stretch without concrete evidence.

The mechanism by which telomeres shorten is complex and not easily reversed, even with oxygen therapy. While HBOT might have some regenerative effects, claiming a 20-year reversal is a stretch without concrete evidence.

The study's vagueness is a problem, but the fact that telomeres can be influenced by oxygen levels isn't entirely out of the question. The real issue is how much of a change they're claiming.

The idea that a 90-day regimen could reverse telomere aging by 20 years ignores the slow, gradual nature of telomere attrition. It’s a huge leap from a study mention to such a definitive claim.

The 20-year age reversal claim is so far outside the realm of what's biologically plausible that it undermines the credibility of the study itself, regardless of the method.

Try frequency, light, and sound.

The claim about a 20-year age difference in telomeres is extraordinary, and the lack of specific study details makes it hard to take seriously. If it were valid, we’d expect more rigorous follow-up, not just a vague reference to a Jerusalem study.

I get the skepticism, but the idea that oxygen could influence cellular aging isn't completely out of the question—just not on the scale claimed.

The idea that oxygen could influence telomeres isn't out of the question, but the scale of the claim—20 years in 90 days—defies basic biology. It's not just about oxygen, it's about the *magnitude* of the effect.