Mainly the sandboxesd apps and profiles. Honestly the inconveniences that bothered me the most were more oddities than privacy features - things like wallpapers and text notifications not fully working on secondary users. I get that fixing some of the small things aren't a priority and it's still a fantastic OS.
I think my initial post was partially in frustration of needing to reconfigure a bunch of stuff to make some simple stuff work. I would still recommend it to anyone who wants a good privacy OS, but not as broadly as some people on nostr recommend it