YES! I love the Barkleys. And I'm from the southeast so I personally know the pain of bushwacking in those hills.
Here it's higher elevation and much more open so it's easier.
The run I have in mind for later this summer is ~35km with a few thousand meters of elevation (mostly loss on this section).
It's the second half of a loop that rings the ridges of a valley here. I don't know if I'll ever be fit enough to do it in one go... 80km and ~8000m of gain/loss in total.
nostr:npub1kuy0wwf0tzzqvgfv8zpw0vaupkds3430jhapwrgfjyn7ecnhpe0qj9kdj8 any interest?