Yes.
I don't have insulin resistance, my insulin response is wicked solid, and I don't consume much fructose (I love fat, sour and bitter, like a good German... sweet isn't my thing). But yes, for many this is the pathway that gave them gout. For me, I was eating lots of lamb -- I raise sheep so it's essentially free food for me. Lots of lamb. So for me, that was probably how I got gout.