This was really interesting. Thank you for sharing! I’ve often thought that incomplete protein decomposition into glucose and waste might contribute as well. Fructose is actually worse for the liver than alcohol, talk about metabolites in the blood serum! As an older man, the more frequent and urgent urination lead me to questions about what my kidneys were trying so desperately to filter from my blood and expel from my body. Fasting helps to secure a place to start in diet experimentation, as our bodies are complex and often it is a combination of multiple factors contributing to the outcome. Eat one thing if that is what it takes, then add and add again. Becoming malnourished as a result of improper nutrition literally takes months, so be brave!

Yes.

I don't have insulin resistance, my insulin response is wicked solid, and I don't consume much fructose (I love fat, sour and bitter, like a good German... sweet isn't my thing). But yes, for many this is the pathway that gave them gout. For me, I was eating lots of lamb -- I raise sheep so it's essentially free food for me. Lots of lamb. So for me, that was probably how I got gout.