Depends on the relay implementation and whether your note has been sent to a relay that doesn’t support deletion.
Discussion
Personally I favour that control at a relay level. Certain data maybe better perishable by default. One of the things that attracted me to NOSTR was an impression of optionality of Permanence I.e. I could create relays to achieve Permanence but the notes were perishable within incomplete structures by design. I saw NOSTR as a treatment layer that could enable experiences that included Permanence.