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Michael Welnick
449326b34b1dc4786d3ad9b52cb7ac23c6a914499476e1eebdb82dcb36085563
I drink tea and I learn things

So with nip29 you create a group at a single relay and then anybody who joins that group will only send events for that group to the relay it belong to?

Is there an up to date list of which clients support which nips?

Posting my Keybase key here just in case

-----BEGIN PGP PUBLIC KEY BLOCK-----

Comment: https://keybase.io/download

Version: Keybase Go 1.0.46 (linux)

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-----END PGP PUBLIC KEY BLOCK-----

I think one of the most important features of github is the "star" count on a repo. Combined with the last commit date, I can tell in a quick glance if a piece of software is actually maintained or if I'll be SOL if there's a bug. There's probably a way to replicate just that part with nostr and then it wouldn't matter where the code is hosted

Replying to Avatar fiatjaf

Yes.

Which relay has this functionality?

So if I select a utxo with 1m sats and set the local amount to 200k I get a channel with 200k on my side and 100k on your side and 800k back to my wallet?

They are clearly dominating in the space, but that P/E ratio is still priced for a lot more growth. Eventually it won’t hit the numbers investors want. When I compare it to DOGE what I mean is that when it finally runs out of steam it could be a good signal that we have reached the top of this bull run in stocks

I suspect the ideas of "insulin resistance" (and it's inverse "insulin sensitivity") are entirely explained by muscle mass and muscle glycogen (and liver glycogen).

I may be wrong; this is my current opinion; I'm not an expert; But this is informed by experts, in particular Roy Taylor, a prominent diabetes researcher from Newcastle University.

If you have a lot of muscle mass and it is depleted of glycogen (generally your liver is also depleted) you are very insulin sensitive. Your muscles will suck up sugar greedily. This happens after fasting, after exercise, and when on the keto diet (essentially a sugar fast). On the other hand, if your muscle and liver glycogen is full then you are insulin resistant. They have no room to suck up any more sugar. You can change your insulin sensitivity quickly, within hours, by eating or fasting. There is a longer-term component and a genetic component, which I presume has to do with how much glycogen your liver and muscles can hold. If you train a lot, they can hold more. But this is also partially genetically determined where some people even after training don't hold much glycogen in their muscles and are thus genetically at least somewhat "insulin resistant" all the time.

People trying to work on their "insulin sensitivity" to avoid type-2 diabetes are IMHO probably misguided. They should just try to be a healthy weight, to not overeat, and to do some exercise to keep their glycogen from filling up and spilling over into body fat.... and ignore this new mysterious thought-to-be-independent factor.

People wearing continuous glucose monitors who aren't diabetic, and even people trying to avoid "blood sugar spikes" by avoiding fruit like bananas, are IMHO also probably misguided. Blood sugar is supposed to spike - that is what insulin is for. Blood sugar spikes don't cause diabetes... it is only high blood sugar that remains high that *signals* diabetes (high blood sugar is an effect of diabetes, not a cause). We evolved to eat fruit and honey for god sake. Epidemiological research shows people that eat a lot of complex carbs live the longest. Gut bacteria need fiber (a carbohydrate) to produce the chemicals that our health seems to depend on.

Diabetes is caused by (based on Roy Taylor's research):

1. Your propensity to store fat viscerally (mostly genetically determined, and widely ranging)

2. Your beta cell tolerance to visceral fat (this also ranges widely and is apparently genetically determined),

3. Based on 1 & 2, if you are over your personal weight threshold such that enough viseral fat has entered your pancreas to cause those beta cells to stop functioning.

Diabetes can be reliably reversed by losing weight... and eating sugar if you want, as long as you lose weight. Roy Taylor reversed diabetes in people by feeding them a complete nutritional supplement (these tend to be 60% carbohydrate) that wasn't enough to meet daily caloric needs, so they lost weight.

There was some clear research based on MRI scans of pancreatic fat that determined that yes, thin people with type-2 diabetes have fat pancreases, even though they don't appear to be fat. And fat people without diabetes don't have fat pancreases. So the connection is pretty clear.

#DontFearTheCarbohydrate

That pretty much sums it up. I haven’t read this book but Iv been following her podcast for a while and I suspect in this book you would find a lot of science to back up your theory https://www.amazon.com/exec/obidos/ASIN/1668007878

Why is M2 going up even with QT going on?

prediction: within 1 year zk rollups and defi on bitcoin will become the biggest topic of discussion on nostr

True, do darknet markets bother with 2 of 3 multisig though?

Yeah the rug pulls happen to the coins that are still locked in escrow. Nostr doesn’t solve the escrow problem

Maybe in very small amounts. Anymore than one cup in the AM is overdoing it. My life has been much better since switching to a high quality matcha. I suspect people are using coffee to overload on cortisol. If you have any stress at all or don’t fall asleep immediately I suggest trying to switch.