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aidan
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Wait, who gave you permission to do that?

No, they were huge from the get-go. I remember it well. Android wasn’t really a thing at that point and in fact completely changed direction with its UX and form factor due to what they saw in the iPhone.

There was a price reduction that occurred quite quickly though, which was a factor in increasing first year sales.

Ok, this was surprisingly good. Gotta admit this adjusted some of my priors.

https://pca.st/episode/3635e2f5-8c4d-49ec-8845-946cfdb655e2

Ambulances being blamed for the accident that they attend to.

Consider that there may be other reasons.

Where we differ is that I believe the evidence shows that high cholesterol *isn’t* necessary or sufficient because it is not causal. It is simply often present where there is CVD, but what’s missed (per the charts above) is that it is very often present *without* any risk of CVD. (And maybe Fibrinogen levels point to the real causal factor — we don’t know)

Read The Clot Thickens by Malcom Kendrick for an alternative view. I don’t believe anyone including Dr Kendrick has the answers, at least yet, but I do believe that we need to accept that we don’t know and humbly pursue the real causes further.

You’d also be dead. It’s like saying if we take cars off the road nobody will die of a road accident.

Look at the prior two charts I posted, which directly show that lowered fibrinogen results in fewer heart attacks *irrespective* of cholesterol levels.

There is no good evidence that lowering cholesterol is an improvement to one’s health. In fact, the opposite may be true.

https://x.com/mangan150/status/1682046284071583745

The truth is that nobody really knows yet what part of the modern lifestyle causes heart attacks, but at this point there’s reasonably strong evidence that cholesterol is not a causal factor.

No mention of lifestyle changes being adopted at the same time the statin is prescribed. 🤔

I find it odd that the simpler studies with statins show no benefit but incredibly complex ones somehow prove their benefit.

Anyway, I think about these charts a lot.

This episode is really great. nostr:note1vychlkh5085q35fxdux9fm69hxrc5u7sz5qsh2kwn3uastra9vwsnqfn0p

If this is the first step in using LLM-generated headlines based on the content within, I’d welcome it.

Editorially-written newspaper headlines are a significant source of audience manipulation.

https://x.com/kyliebytes/status/1693785959526236484?s=46&t=3XVpNzkjKZT1Rzwet4G2Dg

I think aghast is probably a bit strong. I think he’d lean more into educational tools for kids than Tim Cook has, but aside from that not enough has changed since the iPhone 4s/5 for him to be aghast about.

I for one am healthier than I’ve ever been as a direct result of the platforms that smartphones have given rise to.

Unlike tobacco, it’s a tool. A shape-shifting exacto knife that can cause damage to the one who wields it.

The best of times, the worst of times.