The first question I ask when I hear a person is suffering from gout is, have you cut all alcohol consumption? The mechanism for gout is steady levels of blood borne metabolites, uric acid for the most part. With consistent high blood concentrations, in low blood flow areas, the metabolites form crystals much like minerals form stalactites when mineral rich water drips consistently in a cave. These crystals lodge in your joints causing inflammation and pain. Lower the metabolite concentration and the crystals will dissolve.
Discussion
Yeah, unfortunately in my 2 closest cases it's non-drinkers & meat-lovers that got gout.
After eating a bit of a good meat, they couldn't walk the next day. After 1-2 years of diet it got better and now they both can eat meat once in a while without issues.
Next to alcohol, it seems like gout might be related more to insuline resistance and fructose consumption https://tim.blog/2009/10/05/gout/
This was really interesting. Thank you for sharing! I’ve often thought that incomplete protein decomposition into glucose and waste might contribute as well. Fructose is actually worse for the liver than alcohol, talk about metabolites in the blood serum! As an older man, the more frequent and urgent urination lead me to questions about what my kidneys were trying so desperately to filter from my blood and expel from my body. Fasting helps to secure a place to start in diet experimentation, as our bodies are complex and often it is a combination of multiple factors contributing to the outcome. Eat one thing if that is what it takes, then add and add again. Becoming malnourished as a result of improper nutrition literally takes months, so be brave!
Yes.
I don't have insulin resistance, my insulin response is wicked solid, and I don't consume much fructose (I love fat, sour and bitter, like a good German... sweet isn't my thing). But yes, for many this is the pathway that gave them gout. For me, I was eating lots of lamb -- I raise sheep so it's essentially free food for me. Lots of lamb. So for me, that was probably how I got gout.
Your gout is an interesting puzzle where all the usual pieces don’t fit when they usually go. The only thing I can think of is metabolite concentrations are too high because you’re eating too often. Gout as a general condition isn’t exclusively caused by uric acid, though that is the most common culprit. I also wonder if it isn’t caused by something in your water? Personally I would change all my dietary routines drastically one at a time until I found the source of the problem. It might take a while, but gout can be a lifetime lasting painful problem. Worth it!
Yes I cut out alcohol completely. As well as aspirin, yeast, spirulina, baby spinach, parsley, organ meats, and red meat (not that I was eating spirulina or yeast or even parsley which I absolutely hate). Plus my doctor put me on allopurinol. I am confident the monosodium urate crystals will melt away completely within in a few months, now that I know what causes them.
Has the Allopurinol helped? If not, it isn’t likely a uric acid precipitation problem.